Peer-reviewed medical publications

NGS of cell-free DNA in animals

Gordon, Paul MK, et al. Disease-specific motifs can be identified in circulating nucleic acids from live elk and cattle infected with transmissible spongiform encephalopathies. Nucleic Acids Research 37.2 (2009): 550-556.

In a 25-month time-course experiment, CNAs were isolated from blood samples of 24 elk (Cervuselaphus) orally challenged with chronic wasting disease (CWD) infectious material. Our results may become useful for the early diagnosis of TSE in live elk and cattle.

NGS of cell-free DNA in Healthy Humans

Beck, J. et al. Profile of the circulating DNA in apparently healthy individuals. Clin Chem. 2009; 55: 730-8.

Circulating nucleic acids (CNAs) have been shown to have diagnostic utility in human diseases. The use of mass sequencing and bioinformatics provides the basis for new diagnostic approaches that use CNAs as biomarkers for both malignant and nonmalignant diseases.

Using circulating cell-free DNA to monitor personalized cancer therapy

High-quality genomic analysis is critical for personalized pharmacotherapy in patients with cancer

Dr hab. n. med. Jakub Dobruch, FEBU – Liquid Biopsy

Dr hab. n. med. Jakub Dobruch, FEBU. Urological Review, The Polish Association of Urology bimonthly magazine. No. 5/2016

Liquid Biopsy is an example of a new kind of research that could revolutionize cancer detection and treatment of patients affected.

Advanced Cancer Diagnostics Showcasing at 2016 NCRI Cancer Conference 6-9 November 2016

Chronix Biomedical’s Ireland & UK distributors Advanced Cancer Diagnostics will be attending and showcasing the latest Chronix diagnostic tests: Second Opinion CNI Prostate Cancer Test, Second Opinion CNI Breast Cancer Test, CNI Monitor Test.

ASCO 2016

“Tumor cell-free DNA copy number instability (CNI) predicts therapeutic response to immunotherapy prior to cycle 2” , was presented at the American Society of Clinical Oncology (‘ASCO’) Annual Meeting 2016 on 5 June 2016 at [...]