Absolute quantification of graft-derived cell-free DNA as a marker of rejection and graft injury in kidney transplantation – results from a prospective observational trial (Oellerich et al. AACC 2018)

Download PDF

By | August 28th, 2018|Medical publications, Transplant|0 Comments

Schütz E et al. Graft-derived cell-free DNA – a promising rejection marker in cardiac transplantation – Results from a prospective observational trial. 69th AACC Annual Scientific Meeting Abstract eBook (2017):A-121

Download PDF

By | August 28th, 2018|Medical publications, Transplant|0 Comments

Schütz E et al. Graft-derived cell-free DNA a promising Rejection Marker in Liver transplantation Results from a prospective Multicenter Trial. Clin Chem (2016): suppl. A121

Download PDF

By | August 28th, 2018|Medical publications, Transplant|0 Comments

Beck J et al. A new universal multiplex digital PCR method with improved precision for the quantification of donor derived graft DNA traces Clin Chem (2015): suppl

Download PDF

By | August 28th, 2018|Medical publications, Transplant|0 Comments

Beck J et al. Early Detection of Rejection after Heart Transplantation by a universal digital PCR method Clin Chem (2015): suppl

Download PDF

By | August 28th, 2018|Medical publications, Transplant|0 Comments

Beck J et al. Use Of Plasma GcfDNAQuantification To Guide Personalized Immunosuppression. Transplant International 27 (2014): 50

Download PDF

By | August 28th, 2018|Medical publications, Transplant|0 Comments

Beck J et al. Absolute Quantification of Graft derived cell-free DNA (GcfDNA) early after Liver Transplantation (LTx) using droplet Digital PCR. Clin Chem 2015: suppl

Download PDF

By | August 28th, 2018|Medical publications, Transplant|0 Comments

Chronix Biomedical reports positive interim pancreatic cancer data

Chronix Biomedical reports a positive interim analysis of its ongoing validation study of its Copy Number Instability (CNI)-based therapeutic monitoring test in pancreatic cancer. The study compares the accuracy of Chronix’s CNI-based test at predicting a clinical response, as early as after the first cycle of chemotherapy compared to CA19-9, a commonly used biomarker.

By | June 14th, 2017|Chronix news|0 Comments

Predicting Treatment Outcomes in Immunotherapy

Weiss, G. et al. Tumor Cell-Free DNA Copy Number Instability Predicts Therapeutic Response to Immunotherapy.

Genomic analysis of tissue malignancies is well recapitulated by tumor cell free DNA (cfDNA) using the power of Next Generation Sequencing (NGS).

By | May 14th, 2017|Peer-reviewed medical publications|0 Comments

Predicting Treatment Outcomes in Chemotherapy

Weiss, Glen J., et al. Changes in tumor cell-free DNA copy number instability (CNI) predict therapeutic response in metastatic cancers. Cancer Research 76.14 Supplement (2016): 3138-3138.

Gains and losses of chromosomal regions – as a hallmark of cancer – have been detected in plasma as copy number aberrations (CNAs), and for several cancers a relation to tumor size has been reported.

By | May 13th, 2017|Peer-reviewed medical publications|0 Comments