Weiss, Glen J., et al. “Changes in tumor cell-free DNA copy number instability (CNI) predict therapeutic response in metastatic cancers.”Cancer Research 76.14 Supplement (2016): 3138-3138.

Gains and losses of chromosomal regions – as a hallmark of cancer – have been detected in plasma as copy number aberrations (CNAs), and for several cancers a relation to tumor size has been reported.

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